1st symposium on y-chromosome human proteome project
نویسندگان
چکیده
chromosome-centric human proteome project (c-hpp) is a recent initiative to rationalize and analyze gene-protein and protein-protein interactions in normal and disease conditions. this initiative is aimed to generate the proteomic atlas explaining the molecular architecture of the human body and was initiated in response to the hurdles identified during analyzing the human genome project (hgp). a need for the experimental observation of translated proteins was felt to analyze precisely what is going on in the cell. 25 countries around the world are participating in the c-hpp. this symposium report will introduce the y-chromosome hpp which is undergoing in iran by eminent molecular biologists of royan institute, tehran and its collaborates.
منابع مشابه
I-3: Human Y Chromosome Proteome Project 2012 Update
The Human Genome Project has generated a blueprint for the approximately 20,300 gene-encoded proteins potentially active in any of 230 cell types that make up the human body (human proteome). However, based on the UniProtKB/Swiss-Prot database content, about 6000 of at the protein level; for many others, there is very little information related to protein function, abundance, subcellular locali...
متن کامل1stSymposium on Y-Chromosome Human Proteome Project
Received: 24/Feb/2014, Accepted: 7/Jul/2014 Abstract Chromosome-centric human proteome project (C-HPP) is a recent initiative to rationalize and analyze gene-protein and protein-protein interactions in normal and disease conditions. This initiative is aimed to generate the proteomic atlas explaining the molecular architecture of the human body and was initiated in response to the hurdles identi...
متن کاملI-39: Exploring New Frontiers in Human Y Chromosome Proteome Project
The major goal of the Chromosome-Centric Human Proteome Project (C-HPP) is to systematically map the entire human proteome with the intent to enhance our understanding of human biology at the cellular level. However, this goal may be hindered by the lack of quality observations of given proteins due to absence of expression in a given tissue, very low abundance, and expression only in rare samp...
متن کاملI-49: Human Y Chromosome ProteomeProject
The success of the Human Genome Project (HGP) has provided a blueprint for the approximately 20,000 gene-encoded proteins potentially active in all of the hundreds of cell types that make up the human body. Yet we still have limited knowledge about a majority of the gene-encoded proteins which are the “building blocks of life” and “cellular machinery”. It is estimated that for nearly half of th...
متن کاملStandard guidelines for the chromosome-centric human proteome project.
The objective of the international Chromosome-Centric Human Proteome Project (C-HPP) is to map and annotate all proteins encoded by the genes on each human chromosome. The C-HPP consortium was established to organize a collaborative network among the research teams responsible for protein mapping of individual chromosomes and to identify compelling biological and genetic mechanisms influencing ...
متن کاملQuest for Missing Proteins: Update 2015 on Chromosome-Centric Human Proteome Project.
This paper summarizes the recent activities of the Chromosome-Centric Human Proteome Project (C-HPP) consortium, which develops new technologies to identify yet-to-be annotated proteins (termed "missing proteins") in biological samples that lack sufficient experimental evidence at the protein level for confident protein identification. The C-HPP also aims to identify new protein forms that may ...
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عنوان ژورنال:
cell journalجلد ۱۶، شماره ۴، صفحات ۵۶۴-۵۶۷
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